Distance Models for Three-Way Tables and Three-Way Association

p similarity function, the L _p -transform and the Minkowski-p distance. For triadic distance models defined by the L _p -transform we will prove that they do not model three-way association. Moreover, triadic distance models defined by the L _p -transform are restricted multiple dyadic distances, where each dyadic distance is defined for a two-way margin of the three-way table. Distance models for three-way two-mode data, called three-way distance models, do succeed in modeling three-way association.     

最优状态编码研究

探讨了状态机电路最优状态编码的问题。研究了状态编码的成本及寄存器最优、组合逻辑最优之间的关系，介绍了3种常用的编码方法。通过实验分析差异。     

一类连续不可微函数的构造及其Bouligand维数

 利用Buch的方法构造出了一类处处连续,但处处不可微函数,该函数是Buch所构造出的函数的推广,并对该函数图像的盒(Bouligand)维数进行了估计,得出了Buch函数的盒维数只是其中的一种特殊情况.     

微量Mg对纯Ag的性能影响

 在99.995%Ag中添加8×10^-5Mg制成99.99%纯Ag,进行机械性能测试试验.当ε=98%时,在25℃下保存200d,其强度和硬度稳定不变.即在99.995%的高纯Ag中存在有微量镁,使Ag在结晶过程中出现少量Ag溶Mg的固溶体颗粒,细化Ag的晶粒,晶界增多,变形抗力增大.起到强化和稳定机械性能的作用.     

用XML构造法律知识库系统

在分析法律语言及其构造的基础上用XML构造刑法知识库，探讨了XML法律知识库的应用。     

里氏木霉和酵母菌混合发酵玉米秸杆的研究

对里氏木霉和酵母菌混合发酵秸杆提高其粗蛋白含量的发酵工艺进行了研究。结果表明其发酵最优工艺条件 :以尿素作为氮源 ,里氏木霉接种 2 4 h后接种假丝酵母 ,接种量比例为 1∶ 4 (酵母∶里氏木霉 ) ,于 p H3.0 ,30℃下培养 4 d。粗蛋白含量可达 30 .5 5 % ,粗纤维转化率可达 33.5 %。     

濮城油田东区非均质地质的开发与调整措施

以濮城油田东区沙二下储层的沉积相、沉积微相和储层物性解释模型为基础 ,从微观、层内、层间、平面非均质四方面建立了储层分布与储层非均质性三维地质模型 ,并对开发生产调整措施的有效实施提出了建议。由于以上四方面的非均质性总体中等偏强 ,沉积微相的垂向分布、平面展布大小及砂体储油物性的平面变化对非均质性的控制极为明显 ,所以对于不同的沉积微相所对应剩余油量情况采用不同开采方式。对于层间非均质性大的层系 ,可采用有效封堵技术 ,或调整注采压力系统。对平面非均质性大的层系 ,在采用周期性注水或转向注水时对砂体的连续性考虑十分重要     

Sox9 induces testis development in XX transgenic mice.

Mutations in SOX9 are associated with male-to-female sex reversal in humans. To analyze Sox9 function during sex determination, we ectopically expressed this gene in XX gonads. Here, we show that Sox9 is sufficient to induce testis formation in mice, indicating that it can substitute for the sex-determining gene Sry.     

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12).

Retinitis pigmentosa (RP) comprises a clinically and genetically heterogeneous group of diseases that afflicts approximately 1.5 million people worldwide. Affected individuals suffer from a progressive degeneration of the photoreceptors, eventually resulting in severe visual impairment. To isolate candidate genes for chorioretinal diseases, we cloned cDNAs specifically or preferentially expressed in the human retina and the retinal pigment epithelium (RPE) through a novel suppression subtractive hybridization (SSH) method. One of these cDNAs (RET3C11) mapped to chromosome 1q31-q32.1, a region harbouring a gene involved in a severe form of autosomal recessive RP characterized by a typical preservation of the para-arteriolar RPE (RP12; ref. 3). The full-length cDNA encodes an extracellular protein with 19 EGF-like domains, 3 laminin A G-like domains and a C-type lectin domain. This protein is homologous to the Drosophila melanogaster protein crumbs (CRB), and denoted CRB1 (crumbs homologue 1). In ten unrelated RP patients with preserved para-arteriolar RPE, we identified a homozygous AluY insertion disrupting the ORF, five homozygous missense mutations and four compound heterozygous mutations in CRB1. The similarity to CRB suggests a role for CRB1 in cell-cell interaction and possibly in the maintenance of cell polarity in the retina. The distinct RPE abnormalities observed in RP12 patients suggest that CRB1 mutations trigger a novel mechanism of photoreceptor degeneration.